Table 1.
AMA alone | Ery alone | Combined AMA + Ery | Tet alone | Combined AMA + Tet | |||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5 | 10 | 20 | 62.5 | 125 | 250 | 1.25 + 62.5 | 2.5 + 125 | 5 + 250 | 62.5 | 125 | 250 | 1.25 + 62.5 | 2.5 + 125 | 5 + 250 | |
mg/mL | µg/mL | mg/mL + µg/mL | µg/mL | mg/mL + µg/mL | |||||||||||
Escherichia coli ATCC 25922 | 13 | 15 | 18 | 0 | 0 | 0 | 0 | 0 | 0 | 22 | 24 | 27 | 22 | 25 | 28 |
Bacillus cereus ATCC 10702 | 17 | 20 | 23 | 25 | 28 | 30 | 20 | 23 | 27 | 25 | 27 | 31 | 25 | 28 | 32 |
Pseudomonas aeruginosa ATCC 19582 | 16 | 18 | 21 | 26 | 30 | 34 | 21 | 23 | 25 | 22 | 25 | 28 | 25 | 27 | 30 |
Serratia marcescens ATCC 9986 | 0 | 14 | 18 | 0 | 0 | 0 | 0 | 0 | 0 | 16 | 18 | 22 | 15 | 18 | 22 |
Enterococcus faecalis KZN | 17 | 20 | 23 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Staphylococcus aureus OK1 | 17 | 19 | 21 | 28 | 30 | 33 | 25 | 26 | 28 | 31 | 34 | 36 | 30 | 34 | 38 |
Salmonella typhi ATCC 13311 | 25 | 29 | 32 | 0 | 0 | 0 | 0 | 14 | 16 | 29 | 31 | 33 | 31 | 33 | 36 |
Micrococcus luteus | 14 | 16 | 19 | 20 | 23 | 27 | 17 | 20 | 24 | 22 | 26 | 30 | 27 | 30 | 33 |
Proteus vulgaris CSIR 0030 | 18 | 21 | 23 | 22 | 23 | 25 | 22 | 24 | 25 | 23 | 26 | 28 | 25 | 27 | 30 |
Shigella flexneri KZN | 20 | 22 | 24 | 25 | 27 | 30 | 15 | 27 | 31 | 22 | 23 | 25 | 25 | 26 | 28 |
| |||||||||||||||
AMA alone | Met alone | Combined AMA + Met | Amx alone | Combine AMA + Amx | |||||||||||
5 | 10 | 20 | 62.5 | 125 | 250 | 1.25 + 62.5 | 2.5 + 125 | 5 + 250 | 62.5 | 125 | 250 | 1.25 + 62.5 | 2.5 + 125 | 5 + 250 | |
mg/mL | µg/mL | mg/mL + µg/mL | µg/mL | mg/mL + µg/mL | |||||||||||
| |||||||||||||||
Escherichia coli ATCC 25922 | 13 | 15 | 18 | 0 | 15 | 20 | 0 | 15 | 17 | 22 | 24 | 27 | 22 | 24 | 27 |
Bacillus cereus ATCC 10702 | 17 | 20 | 23 | 0 | 0 | 0 | 17 | 20 | 22 | 15 | 18 | 20 | 18 | 20 | 22 |
Pseudomonas aeruginosa ATCC 19582 | 16 | 18 | 21 | 0 | 0 | 0 | 14 | 17 | 19 | 20 | 21 | 22 | 19 | 20 | 22 |
Serratia marcescens ATCC 9986 | 0 | 14 | 18 | 0 | 0 | 0 | 0 | 14 | 18 | 14 | 17 | 20 | 17 | 20 | 23 |
Enterococcus faecalis KZN | 17 | 20 | 23 | 0 | 0 | 0 | 17 | 20 | 23 | 0 | 0 | 0 | 0 | 0 | 0 |
Staphylococcus aureus OK1 | 17 | 19 | 21 | 0 | 0 | 0 | 16 | 21 | 24 | 28 | 30 | 32 | 27 | 29 | 32 |
Salmonella typhi ATCC 13311 | 25 | 29 | 32 | 0 | 0 | 0 | 0 | 15 | 18 | 28 | 32 | 34 | 30 | 35 | 37 |
Micrococcus luteus | 14 | 16 | 19 | 0 | 0 | 0 | 11 | 14 | 16 | 28 | 32 | 36 | 33 | 36 | 40 |
Proteus vulgaris CSIR 0030 | 18 | 21 | 23 | 0 | 0 | 0 | 14 | 16 | 18 | 18 | 20 | 22 | 20 | 23 | 2 |
Shigella flexneri KZN | 20 | 22 | 24 | 0 | 0 | 0 | 15 | 18 | 20 | 19 | 20 | 23 | 22 | 25 | 26 |
| |||||||||||||||
AMA alone | Cip alone | Combined AMA + Cip | Nal alone | Combined AMA + Nal | |||||||||||
5 | 10 | 20 | 1.25 | 2.5 | 5 | 1.25 + 1.25 | 2.5 + 2.5 | 5 + 5 | 62.5 | 125 | 250 | 1.25 + 62.5 | 2.5 + 125 | 5 + 250 | |
mg/mL | µg/mL | mg/mL + µg/mL | µg/mL | mg/mL + µg/mL | |||||||||||
| |||||||||||||||
Escherichia coli ATCC 25922 | 13 | 15 | 18 | 30 | 33 | 35 | 20 | 24 | 27 | 25 | 27 | 30 | 20 | 24 | 28 |
Bacillus cereus ATCC 10702 | 17 | 20 | 23 | 20 | 24 | 27 | 18 | 22 | 27 | 20 | 25 | 28 | 17 | 19 | 22 |
Pseudomonas aeruginosa ATCC 19582 | 16 | 18 | 21 | 21 | 25 | 28 | 18 | 21 | 25 | 24 | 27 | 30 | 17 | 19 | 24 |
Serratia marcescens ATCC 9986 | 0 | 14 | 18 | 32 | 35 | 40 | 26 | 29 | 32 | 27 | 30 | 33 | 25 | 28 | 30 |
Enterococcus faecalis KZN | 17 | 20 | 23 | 33 | 38 | 42 | 21 | 24 | 28 | 0 | 0 | 0 | 0 | 0 | 0 |
Staphylococcus aureus OK1 | 17 | 19 | 21 | 30 | 35 | 38 | 25 | 27 | 30 | 0 | 0 | 0 | 15 | 18 | 21 |
Salmonella typhi ATCC 13311 | 25 | 29 | 32 | 32 | 37 | 40 | 15 | 16 | 18 | 29 | 32 | 34 | 24 | 26 | 29 |
Micrococcus luteus | 14 | 16 | 19 | 23 | 28 | 32 | 19 | 24 | 27 | 0 | 0 | 0 | 0 | 0 | 0 |
Proteus vulgaris CSIR 0030 | 18 | 21 | 23 | 25 | 26 | 28 | 23 | 25 | 27 | 24 | 26 | 30 | 23 | 25 | 29 |
Shigella flexneri KZN | 20 | 22 | 24 | 28 | 30 | 33 | 30 | 32 | 35 | 18 | 20 | 22 | 20 | 21 | 23 |
| |||||||||||||||
AMA alone | Chl alone | Combined AMA + Chl | Kan alone | Combined AMA + Kan | |||||||||||
5 | 10 | 20 | 62.5 | 125 | 250 | 1.25 + 62.5 | 2.5 + 125 | 5 + 250 | 62.5 | 125 | 250 | 1.25 + 62.5 | 2.5 + 125 | 5 + 250 | |
mg/mL | µg/mL | mg/mL + µg/mL | µg/mL | mg/mL + µg/mL | |||||||||||
| |||||||||||||||
Escherichia coli ATCC 25922 | 13 | 15 | 18 | 22 | 25 | 30 | 16 | 19 | 21 | 23 | 25 | 28 | 16 | 20 | 23 |
Bacillus cereus ATCC 10702 | 17 | 20 | 23 | 25 | 28 | 30 | 19 | 20 | 24 | 24 | 27 | 30 | 15 | 17 | 21 |
Pseudomonas aeruginosa ATCC 19582 | 16 | 18 | 21 | 25 | 28 | 30 | 20 | 22 | 26 | 22 | 25 | 28 | 20 | 23 | 26 |
Serratia marcescens ATCC 9986 | 0 | 14 | 18 | 0 | 0 | 0 | 16 | 20 | 24 | 23 | 25 | 28 | 19 | 24 | 26 |
Enterococcus faecalis KZN | 17 | 20 | 23 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
Staphylococcus aureus OK1 | 17 | 19 | 21 | 21 | 25 | 28 | 17 | 20 | 23 | 18 | 22 | 27 | 22 | 26 | 28 |
Salmonella typhi ATCC 13311 | 25 | 29 | 32 | 30 | 32 | 35 | 23 | 27 | 30 | 28 | 30 | 32 | 29 | 32 | 34 |
Micrococcus luteus | 14 | 16 | 19 | 29 | 30 | 35 | 20 | 24 | 27 | 22 | 25 | 28 | 20 | 24 | 26 |
Proteus vulgaris CSIR 0030 | 18 | 21 | 23 | 25 | 28 | 30 | 25 | 26 | 28 | 23 | 26 | 28 | 25 | 27 | 29 |
Shigella flexneri KZN | 20 | 22 | 24 | 25 | 27 | 29 | 25 | 26 | 28 | 19 | 23 | 25 | 23 | 25 | 27 |
AMA: acetone extract of A. mearnsii; Ery: erythromycin; Tet: tetracycline; Met: metronidazole; Cip: ciprofloxacin; Nal: nalidixic acid; Chl: chloramphenicol; Kan: kanamycin.