Table 5.
Comparison of blood pressure, anthropometric characteristics, and classic or not biomarkers between women with normal blood pressure in pregnancy (NBPP) and preeclamptic women (PE) according to Haptoglobin phenotype.
| Hp 1.1 plus 2.1 | Hp 2.2 | |||||
|---|---|---|---|---|---|---|
| NBPP n (mean ± SD) |
PE n (mean ± SD) |
P value | NBPP n (mean ± SD) |
PE n (mean ± SD) |
P value | |
| BMI (Kg/m2)† | 41 (25.18 ± 3.80) | 57 (26.95 ± 5.46) | 0.061 | 18 (25.90 ± 4.65) | 31 (27.23 ± 3.32) | 0.249 |
| WC (cm)† | 38 (82.43 ± 10.0) | 57 (90.78 ± 17.58) | 0.004 | 18 (83.47 ± 9.84) | 31 (87.26 ± 11.15) | 0.238 |
| Systolic BP (mmHg)† | 40 (119.18 ± 13.67) | 57 (134.65 ± 18.31) | <0.001 | 18 (118.22 ± 13.01) | 31 (135.61 ± 12.79) | <0.001 |
| Diastolic BP (mmHg)† | 40 (72.80 ± 11.18) | 57 (86.19 ± 19.42) | <0.001 | 18 (70.89 ± 7.15) | 31 (85.45 ± 16.26) | <0.001 |
| Pulse pressure† | 40 (46.38 ± 8.12) | 57 (48.46 ± 11.89) | 0.308 | 18 (47.33 ± 11.76) | 31 (50.16 ± 12.07) | 0.429 |
| CRP (mg/L)†† | 38 (0.40 ± 0.15) | 55 (0.50 ± 0.10) | 0.697 | 18 (0.40 ± 0.12) | 28 (0.70 ± 0.09) | 0.106 |
| MPO (ng/mL)† | 17 (57.89 ± 32.47) | 18 (94.17 ± 42.14) | 0.008 | 7 (72.89 ± 25.64) | 14 (74.75 ± 33.89) | 0.900 |
| Nitrites (μmol/L)† | 18 (9.57 ± 3.19) | 18 (19.98 ± 8.53) | <0.001 | 7 (11.54 ± 5.06) | 14 (18.01 ± 4.44) | 0.007 |
| NOx (μmol/L)† | 18 (79.04 ± 37.15) | 17 (101.32 ± 48.79) | 0.141 | 7 (79.53 ± 43.39) | 12 (96.79 ± 22.34) | 0.356 |
| AST (UI/L)†† | 41 (18.00 ± 0.70) | 59 (19.00 ± 0.66) | 0.084 | 19 (8.00 ± 1.40) | 31 (19.00 ± 1.67) | 0.582 |
| ALT (UI/L)†† | 41 (15.00 ± 1.13) | 59 (18.00 ± 1.04) | 0.005 | 19 (19.00 ± 2.11) | 31 (20.00 ± 3.34) | 0.234 |
| t-Cholesterol (mg/dL)† | 41 (203.73 ± 33.24) | 59 (202.66 ± 38.65) | 0.886 | 19 (212.68 ± 36.63) | 31 (215.77 ± 39.81) | 0.785 |
| Non HDL cholesterol† | 40 (155.58 ± 35.59) | 59 (153.97 ± 37.03) | 0.830 | 19 (160.00 ± 36.41) | 31 (166.16 ± 39.03) | 0.581 |
| LDL (mg/dL)† | 40 (137.90 ± 33.04) | 59 (133.90 ± 33.04) | 0.523 | 19 (140.53 ± 31.49) | 31 (146.29 ± 37.61) | 0.579 |
| HDL (mg/dL)† | 40 (49.00 ± 1.31) | 59 (49.00 ± 1.08) | 0.954 | 19 (56.00 ± 1.95) | 31 (49.00 ± 1.59) | 0.203 |
| Apo A (mg/dL)† | 41 (0.90 ± 0.17) | 58 (0.98 ± 0.16) | 0.011 | 17 (1.07 ± 0.22) | 29 (1.02 ± 0.19) | 0.405 |
| Apo B (mg/dL)† | 41 (0.58 ± 0.12) | 58 (0.62 ± 0.14) | 0.122 | 17 (0.61 ± 0.15) | 29 (0.68 ± 0.13) | 0.105 |
†Independent sample t-test; and values are means ± standard deviation (SD).
††Mann-Whitney U test; and values are median ± standard error (SE).
Body mass index (BMI), waist circumference (WC), systolic blood pressure (Systolic BP), diastolic blood (Diastolic BP), pulse pressure, c-reactive protein (CRP), myeloperoxidase (MPO), nitrites, total nitric oxide metabolites (NOx), aspartate transaminase (AST), alanine transaminase (ALT), total cholesterol (t-cholesterol), non HDL cholesterol, low density lipoprotein (LDL), high density lipoprotein (HDL), Apolipoprotein A and B (Apo B and Apo A).