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. 2014 Jul;20(3):318–325. doi: 10.5056/jnm13098

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©2014 The Korean Society of Neurogastroenterology and Motility

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 4. — Electrical field stimulation (EFS)-induced response of the rat gastric fundus circular muscle strips after serial administration of atropine, DA-9701, N-nitro-L-arginine (L-NNA), MRS2500 and tetrodotoxin (TTX). (A, B) When atropine was added, peak was decreased and nadir was increased by inhibiting contraction (^*P < 0.05, by Wilcoxon signed ranks test). (C, D) When DA-9701 (0.5, 5, 25 and 50 μg) was added in the presence of atropine, peak and nadir did not show significant dose-dependent changes (Kruskal Wallis test for testing differences in EFS-induced contractile responses for different DA-9701 doses). (E, F) Subsequent addition of L-NNA, MRS2500 and TTX in the presence of atropine and DA-9701 (50 μg) did not affect peak and nadir (compared with previous value by Wilcoxon signed ranks test).