Obese CXCR3-deficient mice exhibit decreased expression of inflammation-related genes in their peri-epididymal adipose tissue, compared to obese wild-type mice. mRNA levels of MCP-1, RANTES, IFNγ, ARG1, Foxp3, and IL-10 in adipose tissue from CXCR3-deficient mice (black bars) and control mice (gray bars) at 8 weeks (A) and at 16 weeks of high-fat diet (HFD) (B) were quantified by RT-qPCR and normalized to GAPDH mRNA expression. Fold change was calculated relative to wild-type controls. *p<0.05 vs. wild-type controls; n=6/group.