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Schematic representation of sandwich DNA detection assay via AuNP-mediated SPR signal amplification. The SPR measurements were carried out by injecting the oligonucleotide functionalized AuNPs into the flow cell housing sensors covered with various duplexes or capture probes. The intermediate dextran layer reduces the nonspecific adsorption of AuNPs, improving detection sensitivity. Adapted from Ref 961.
