Table 3. Significant associations between variation in SNPs and likelihood of melanoma.
Loci | SNP | Minor Allele | Major Allele | MAF | OR (95% CI) | Pa | OR (95% CI) | Pb |
---|---|---|---|---|---|---|---|---|
ANKK1 | rs12360992 | A | C | 0.45 | 1.16 (1.01, 1.33) | 0.03 | 1.18 (1.02, 1.35) | 0.02 |
ANKK1 | rs1003641 | A | G | 0.30 | 1.17 (1.00, 1.36) | 0.05 | 1.20 (1.03, 1.40) | 0.02 |
DRD2 | rs2734831 | A | C | 0.39 | 1.18 (1.02, 1.35) | 0.03 | 1.17 (1.02, 1.35) | 0.03 |
DRD2 | rs44365781 | G | A | 0.12 | 1.26 (1.00, 1.59) | 0.05 | 1.27 (1.01, 1.60) | 0.05 |
DRD2 | rs4648318 | G | A | 0.25 | 1.19 (1.00, 1.40) | 0.05 | 1.20 (1.02, 1.42) | 0.03 |
P-value, crude.
P-value, adjustment for age, sex and phenotypic index.
Association was tested using a dominant model.