Figure 6. iTReg from Sb^R-LD-PBMC mediates their suppressive activity through IL-10 and TGF- β.

Percentages of rLAP (TGF-β1) containing iTreg cells from Sb^S-LD-PBMC and Sb^R-LD-PBMC at day eight are represented. A, B. Percentage of LAP (TGF-β1)⁺ iTreg cells on day eight. Pseudo colour plot indicate one representative data set. C. Suppression assay in presence of neutralizing IL-10 antibody and/or rLAP. Data were analysed by Mann-Whitney test and two-tailed paired student t test, and levels of significance are indicated by P values.