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. Author manuscript; available in PMC: 2014 Jul 17.
Published in final edited form as: Mol Carcinog. 2009 Nov;48(11):995–1004. doi: 10.1002/mc.20551

FIGURE 2.

FIGURE 2

Ron deletion significantly increases the number of ApcMin/+ mice with high tumor burden, but does not impact mean tumor number or distribution. ApcMin/+ mice were crossed with RonTK+/− mice to generate ApcMin/+;RonTK+/+ and ApcMin/+;RonTK−/−mice. Intestinal tumors were analyzed at three months of age. A) The mean number of tumors per mouse and within each segment of the gastrointestinal tract (duodenum, jejunum, ileum, and colon) per genotype (n=13). p>0.05 for all comparisons between genotypes, Wilcoxon rank-sum test. B) The mean number of tumors per mouse is plotted per genotype (n=13). Each data point represents a single mouse; the median tumor number in ApcMin/+;RonTK+/+ controls is denoted (29, black line). p=0.0017, binomial test.