Table 2. Revised Brunet-Lezine development quotient scores related to perinatal mother-to-child Chikungunya virus infection, CHIMERE cohort, Reunion Island, 2008.
Exposure group | Unexposed Uninfected children (n = 65) | Exposed Uninfected children (n = 70) | Exposed Infected children (n = 33) | ||||
DQ scores | mean | (95% CI) | mean | (95% CI) | mean | (95% CI) | P value |
Global | 100.1 | (96.6–113.1) | 100.4 | (97.5–114.3) | 86.3 | (81.2–93.5) | <0.001 |
Movement/Posture | 111.3 | (107.1–123.4) | 115.5 | (112.0–128.5) | 98.5 | (91.0–105.3) | <0.001 |
Coordination | 93.6 | (90.3–107.0) | 95.8 | (92.4–117.1) | 83.5 | (76.0–90.9) | <0.001 |
Language | 97.7 | (93.1–110.9) | 94.1 | (90.6–108.5) | 80.0 | (74.8–87.5) | <0.001 |
Sociability | 105.5 | (101.0–118.2) | 103.0 | (99.0–116.8) | 90.5 | (84.2–97.5) | 0.001 |
DQ: development quotient. DQ scores were measured between 15.8 and 27 months of age. Developmental delay is moderate if. †85≤DQ ≤70, severe if. ‡DQ score <70.
Data are means and 95% confidence intervals. P values are given for Kruskal-Wallis or Fisher exact tests comparing the three groups:
P value<0.01 for Fisher exact test comparing unexposed uninfected versus infected children:
**P value<0.01 for Fisher exact test comparing exposed uninfected versus infected children.