. 2014 Jul 17;8(7):e2999. doi: 10.1371/journal.pntd.0002999

Table 1. Activity of MF against promastigotes and intracellular amastigotes of L. amazonensis wild-type strains and mutant MF150.3-1.

	Promastigotes		Amastigotes
	Survival		% Infection^a		Number of intracellular amastigotes^b
	EC₅₀ ^c	EC₉₀	EC₅₀	EC₉₀	EC₅₀	EC₉₀
*L. amazonensis* M2269	19.9±2.2	34.0	2.8±1.1	14.4	2.4±1.2	12.5
*L. amazonensis* 2506	47.0±3.9	64.1	12.7±4.1	23.5	10.6±4.2	32.8
MF150.3-1	167.3±16.8	204.3	>40	ND^d	>40	ND

EC₅₀ determined according to the percentage of infection.

EC₅₀ determined according to the average number of amastigotes per infected macrophage.

EC₅₀ ± standard deviation in µM. Results are the average of at least three independent experiments.

ND: not determined.