Figure 5. Neutralization of the IFN response during RSV-A2-GFP infection.

The effects of neutralization of IL-28A, IL-28B/IL-29 and IFN-β following RSV infection were assessed. GFP⁺ surface area was used to assess the degree of RSV infection (A) and quantitative immunofluorescence was used to determine the balance of acetylated α-tubulin⁺ and MUC5AC⁺ cells. Mean data ± SEM are shown from 10–14 inserts over 4–6 independent experiments, respectively. Statistical significance was determined with a one way ANOVA statistical test with post-hoc Dunnetts test compared to untreated control cells, ***p<0.001.