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. 2014 Jul 17;9(7):e102814. doi: 10.1371/journal.pone.0102814

Table 3. The results of two way ANOVA (with the given signal parameter being the dependent variable and age and the subject group being the two independent variables).

47÷63 y.o. 64÷78 y.o. p-value
No. Parameter Mean±SD Mean±SD Levene’s test Age Group (≤63 &>63 y.o.) Subject Group (CG,GODA, POAG, PACG) Interaction SubjectGroup & Age
1 τ (ECG, BPL) [s] 0.28±0.03 0.31±0.07 0.02 - - -
2 τ (ECG, maxCIP1) [s] 0.16±0.04 0.18±0.05 0.41 <0.001 0.20 0.41
3 τ (ECG, maxCIP2) [s] 0.57±0.12 0.64±0.14 0.46 0.003 0.39 0.62
4 τ (BPL, maxCIP1) [s] 0.12±0.05 0.13±0.07 0.03 - - -
5 τ (BPL, maxCIP2) [s] 0.29±0.12 0.33±0.12 0.16 0.06 0.05 0.68
6 pre CT [s] 0.12±0.03 0.13±0.04 0.34 0.001 0.08 0.31
7 CT [s] 0.25±0.09 0.30±0.11 0.22 0.06 0.05 0.91
8 pre RCT [%] 16±5 16±4 0.04 - - -
9 RCT [%] 33±11 34±12 0.07 0.96 0.13 0.68
10 HR [beat/min] 79±10 71±11 0.14 <0.001 0.40 0.01

Statistically significant differences satisfying the criterion of equality of variances are marked in bold font.

CG – control group; GODA – glaucoma suspects with glaucomatous optic disc appearance; POAG – primary open angle glaucoma; PACG – primary angle closure glaucoma; τ(ECG, BPL) – time delay between R wave peak of ECG and systolic BPL peak; τ(ECG, maxODP1) – time delay between R wave peak of ECG and the first major ODP maximum; τ(ECG, maxODP2) – time delay between R wave peak of ECG and the second major ODP maximum; τ(BPL, maxODP1) – time delay between systolic BPL peak and the first major ODP maximum; τ(BPL, maxODP2) – time delay between systolic BPL peak and the second major ODP maximum; preCT – preliminary crest time - time taken from minimum to the first major maximum of ODP shape; CT – crest time - time taken from minimum to maximum of ODP shape; HCT – time duration of heart cycle, taken from R peak to the next R peak of ECG shape; preRCT = preCT/HCT*100% – preliminary relative crest time; RCT = CT/HCT*100% – relative crest time and HR – the heart rate.