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. Author manuscript; available in PMC: 2015 Jul 29.
Published in final edited form as: J Mol Biol. 2014 May 27;426(15):2886–2899. doi: 10.1016/j.jmb.2014.05.022

Figure 6. IBMPFD/ALS p97 mutations affect potency of ML240 and ML241.

Figure 6

Figure 6

(A) ATPase activities of WT p97 and the A232E disease mutant (with Walker B mutations) indicated that the elevated ATPase activity originated from D2. (B) Inhibition of ATPase activity of WT p97 and eight disease mutants by ML240 and ML241.