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. Author manuscript; available in PMC: 2015 Jul 1.
Published in final edited form as: Circ Heart Fail. 2014 May 29;7(4):627–633. doi: 10.1161/CIRCHEARTFAILURE.114.001129

Figure 3.

Figure 3

Ranolazine significantly reduced maximum rate of rise of the action potential upstroke (Vmax; A) and conduction velocity (B; estimated from the duration of the P wave and QRS duration) as well as increased diastolic threshold of excitability (DTE; C) in atrial but not in ventricular preparations isolated from dogs with heart failure. Cycle length=500 ms. n=6-10. *p<0.05 vs control (pairted t-test). Means±SD.