Table 1.
Demographic Data and Baseline Characteristics by treatment modality
| All Dietary Therapy (n = 31) |
Targeted (n = 22) |
SFED (n = 9) |
|
|---|---|---|---|
| Age (mean years ±SD) | 36±9 | 38±9 | 33±8 |
| Female (n, %) | 16 (52) | 12 (55) | 4 (44) |
| White race (n, %) | 28 (90) | 19 (86) | 9 (100) |
| Atopic Disease (any) (n, %) | 26 (84) | 19 (86) | 7 (78) |
| Skin Prick Testing | |||
| Positive for Food (n, %)*, † | 24 (80) | 21 (95) | 3 (38) |
| Positive for Environmental (n, %)† | 24 (96) | 18 (95) | 6 (100) |
| Laboratory Values | |||
| Elevated ESR or CRP (n, %) | 2 (6) | 2 (9) | 0 (0) |
| IgE (mean kU/L ±SD) | 342 ±340 | 389 ±377 | 188 ±100 |
| Peripheral Eosinophils (cells × 109/L ±SD)‡ | 0.42 ±0.44 | 0.46 ±0.12 | 0.13 ±0.13 |
| Presenting Symptoms (n, %) | |||
| Dysphagia | 28 (90) | 20 (91) | 8 (89) |
| Food Impaction | 11 (35) | 9 (41) | 2 (22) |
| Heartburn | 15 (48) | 11 (50) | 4 (44) |
| Chest Pain | 12 (39) | 9 (41) | 3 (33) |
| Abdominal Pain | 7 (23) | 5 (23) | 2 (22) |
| Nausea | 3 (10) | 2 (9) | 1 (11) |
| Vomiting | 3 (10) | 3 (14) | 0 (0) |
| Baseline Endoscopic Findings (n, %) | |||
| Normal | 2 (6) | 1 (5) | 1 (11) |
| Rings | 21 (68) | 16 (73) | 5 (56) |
| Stricture | 7 (23) | 3 (14) | 4 (44) |
| Narrowing | 14 (45) | 9 (41) | 5 (55) |
| Furrows | 23 (74) | 16 (73) | 7 (78) |
| Crêpe Paper | 1 (3) | 0 (0) | 1 (11) |
| White Plaques | 14 (45) | 10 (45) | 4 (44) |
| Decreased Vascularity | 10 (32) | 7 (32) | 3 (33) |
| Erosive esophagitis | 2 (6) | 2 (9) | 0 (0) |
| Hiatal Hernia | 2 (6) | 1 (5) | 1 (11) |
| Dilation Performed | 9 (29) | 6 (27) | 3 (33) |
*
Fisher’s exact p = 0.002 for the comparison between the targeted and SFED groups
†
Proportions are based on the 30 patients who underwent food allergen sensitivity testing (22 in the targeted group and 8 in the SFED group) and 25 who underwent testing for environmental allergen sensitivities (19 in the targeted group and 6 in the SFED group)
‡
Wilcoxon exact p = 0.06 for the comparison between the targeted and SFED groups