Table 3.
<15 eos/hpf (n = 11) |
≥15 eos/hpf (n = 17) |
p-value | |
---|---|---|---|
Age (mean years ± SD) | 38±7 | 34±10 | 0.35 |
Female (n, %) | 7 (64) | 7 (41) | 0.44 |
White (n, %) | 10 (91) | 16 (100) | 0.41 |
Atopic Disease (n, %) | 10 (91) | 13 (76) | 0.62 |
Skin Prick Testing | |||
Positive for Food (n, %) | 7 (70) | 14 (82) | 0.64 |
Positive for Environmental (n, %) | 9 (100) | 13 (93) | 1.00 |
Laboratory Values | |||
Elevated ESR or CRP (n, %) | 0 (0) | 2 (12) | 0.68 |
Peripheral Eos (mean cells × 109/L ± SD) | 0.46±0.59 | 0.40±0.37 | 0.64 |
IgE (mean kU/L ± SD) | 142±94 | 468±383 | 0.03 |
Presenting Symptoms (n, %) | |||
Dysphagia | 9 (82) | 16 (94) | 0.54 |
Food Impaction | 5 (45) | 6 (35) | 0.70 |
Heartburn | 5 (45) | 9 (53) | 1.00 |
Chest pain | 4 (36) | 7 (41) | 1.00 |
Abdominal Pain | 2 (18) | 4 (24) | 1.00 |
Vomiting | 0 (0) | 2 (12) | 0.51 |
Nausea | 1 (9) | 2 (12) | 1.00 |
Endoscopic findings (n, %) | |||
Normal | 1 (9) | 0 (0) | 0.39 |
Rings | 9 (82) | 10 (59) | 0.25 |
Stricture | 1 (9) | 6 (35) | 0.19 |
Narrowing | 4 (36) | 10 (59) | 0.44 |
Furrows | 9 (82) | 12 (71) | 0.67 |
Crêpe Paper | 0 (0) | 1 (6) | 1.00 |
White Plaques | 5 (45) | 8 (47) | 1.00 |
Decreased Vascularity | 3 (27) | 7 (41) | 0.69 |
Erosive esophagitis | 0 (0) | 2 (12) | 0.51 |
Hiatal Hernia | 0 (0) | 2 (12) | 0.51 |
Dilation Performed | 4 (36) | 5 (29) | 1.00 |
Baseline Max Eosinophil Count (mean eos/hpf ± SD) | 53±23 | 95±94 | 0.20 |
Dietary Therapy Characteristics (n, %) | |||
Targeted Diet | 6 (55) | 13 (76) | 0.41 |
Tried multiple diets | 3 (30) | 3 (19) | 1.00 |
Indication for Dietary Therapy | 0.58 | ||
Dietary therapy and no prior steroid therapy | 3 (27) | 3 (18) | |
Dietary therapy after steroid response‡ | 7 (64) | 9 (53) | |
Dietary therapy after steroid failure‡ | 1 (9) | 5 (29) |
3 patients who did not undergo repeat upper endoscopy to assess response are not included
Response defined as < 15 eos/hpf on swallowed steroid; failure defined as ≥15 eos/hpf on swallowed steroids