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. Author manuscript; available in PMC: 2015 Dec 1.
Published in final edited form as: Magn Reson Med. 2014 Jan 17;72(6):1702–1711. doi: 10.1002/mrm.25082

Figure 6.

Figure 6

A) WM-GM susceptibility contrast dependence on white matter fiber orientation and Gd concentration at 7.0 T in the anterior commissure. Field-parallel fibers are sparsely represented in the image data due to the scan orientation of the specimens. For each specimen, one-parameter linear regression was used to find the mean susceptibility contrast as a function WM fiber orientation only. A two-parameter regression model was used to find mean susceptibility contrast as a function of both fiber orientation and Gd concentration. The simulated data was generated from the three-pool WM fiber model. B) WM susceptibility anisotropy as a function of Gd concentration in the anterior commissure. Susceptibility anisotropy is increased by more than six-fold at the highest Gd concentration used in this study. Both models are highly correlated with the measured anisotropy.