Table 2.

Risk and prognostic factors for chronic GVHD

Factor	Reference
Established risk factors
Previous acute GVHD, HLA disparities, recipient’s and donor’s age, peripheral blood stem cells, T-cell replete graft, controversial risk factors, male recipient/multiparous female donor, cord blood stem cells, viral infection, conditioning regimen	62
Prognostic factors	62
Thrombocytopenia, type of disease onset (progressive and overlap syndrome), extensive skin involvement, elevated bilirubin, lung involvement, gastrointestinal involvement (diarrhea), decreased performance status
Prognostic classifications	18
Limited vs extensive	79, 81
Johns Hopkins Hospital	59
Center for International Blood and Marrow Transplant Research	61, 63
NIH consensus classification	4