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. 2014 Mar 16;5(10):3076–3087. doi: 10.18632/oncotarget.1832

Figure 1. A) Gene expression changes in response to 5-Aza-2'-deoxycytidine treatment in parental MDA-MB-231 breast cancer cell line and MDA-MB-231 BR and MDA-MB-231 SA variants.

Figure 1

The number before brackets defines the genes up-regulated in each cell line after 5-Aza-2'-deoxycytidine treatment. The number in brackets defines the number of genes also down-regulated in the brain metastases as compared to non-relapsed primary tumors. Figure 1B) Expression of CADM1, RECK, CXCL14, SPARC and TNFAIP3 in BCBM samples relative to primary breast tumors (PT). HR pos.: estrogen and progesterone positive receptor, TNBC: triple negative breast cancer. P- values were determined by the log rank test.