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. 2014 Apr 27;5(10):3246–3260. doi: 10.18632/oncotarget.1922

Figure 2. Effect of PEG-LD and free doxorubicin on C4-HI tumor growth.

Figure 2

Top: Growth curves. Syringes represent injections. With doses of 18 mg/kg, complete tumor regression was observed with both formulations. With doses of 9 mg/kg, PEG-LD showed an improved effect compared with free doxorubicin; a vs. b: p<0.05; ***: p<0.001 experimental vs. control. Bottom: histological images of tumors treated with 18 mg/kg PEG-LD for one month. Few residual neoplastic cells remained immersed in a dense hyaline stroma (arrow); bar = 100 μm.