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. 2014 Mar 15;28(4):275–281. doi: 10.7555/JBR.28.20120075

Fig. 4. xIRE1α knockdown rescued the apoptosis in embryos of stage 18 with TM treatment by TUNNEL.

Fig. 4

A: The control embryos without TM treatment showed few staining indicating apoptosis (arrow). B: The TM-treated embryos showed significant signal for apoptosis (arrows). C: The embryos were injected with 50 ng of IRE1αMO at 4 cell stage, then treated with TM, and the apoptotic signal was decreased (arrows). D: A quantitative presentation is given. E: Expression of CHOP is inhibited in TM-treated embryos and rescued by xIRE1α knockdown. *P < 0.05 compared with control embryos.