Table 5.
Multi-level model for HLA-DRB1*03:01 dosage over phenotype
Phenotype | Effect (change in dosage) | 95% CI | P-value |
---|---|---|---|
(A) Results for anti-Ro | |||
Anti-Ro( −)/control | 0.10 | 0.08–0.13 | 1.97 × 10 −14 |
Anti-Ro( +)/anti-Ro(−) | 0.27 | 0.22–0.31 | 2.97 × 10 −33 |
(B) Results for anti-La | |||
Anti-La( −)/control | 0.13 | 0.11–0.15 | 3.57 × 10 −25 |
Anti-La( +)/anti-La( −) | 0.41 | 0.35–0.47 | 2.45 × 10 −39 |
Abbreviation: CI, confidence interval. Effect is the change in dosage for HLA-DRB1*03:01 between positive and negative for specified phenotype. (A) Results for healthy control/anti-Ro-negative/anti-Ro-positive. (B) Results healthy control/anti-La-negative/anti-La-positive.