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. 2014 Jul 18;5:340. doi: 10.3389/fimmu.2014.00340

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Copyright © 2014 O’Connell, Volpi, Dobbs, Fiorini, Tsitsikov, de Boer, Barlan, Despotovic, Espinosa-Rosales, Hanson, Kanariou, Martínez-Beckerat, Mayorga-Sirera, Mejia-Carvajal, Radwan, Weiss, Pai, Lee and Notarangelo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Analysis of somatic hypermutation. The rate (per 1,000 nucleotides) of somatic hypermutation in complementarity determining regions (CDR) and framework regions (FR) is shown for controls and WAS patients. Bars indicate the mean ± SD.