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. 2014 Jul 18;5:340. doi: 10.3389/fimmu.2014.00340

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Copyright © 2014 O’Connell, Volpi, Dobbs, Fiorini, Tsitsikov, de Boer, Barlan, Despotovic, Espinosa-Rosales, Hanson, Kanariou, Martínez-Beckerat, Mayorga-Sirera, Mejia-Carvajal, Radwan, Weiss, Pai, Lee and Notarangelo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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TRBV gene usage in CD4⁺ naive and memory lymphocytes from healthy controls and patients with WAS. The frequency of usage of individual TRBV genes in unique TRB sequences is displayed for CD4⁺ naïve (top panel) or memory (bottom panel) lymphocytes. The blue line indicates the average frequency of the two control patients, and the error bars indicate the SD of the frequency of the controls.