Table 2.
Power Summary using the global-rank endpoint with all-cause death, HF hospitalization, and difference (Δ) in NT-proBNP
| Time- averaged Δ NT-proBNP |
Power for the Δ NT-proBNP Endpoint |
Global Rank Power (RRR* of 20%) |
Power for the Clinical Endpoint with RRR of 20% |
Global Rank Power (RRR of 25% |
Power for Clinical Endpoint with RRR of 25% |
|---|---|---|---|---|---|
| 0.4 SD | 92% | 74% | 21% | 83% | 31% |
| 0.5 SD | 98% | 86% | 21% | 92% | 31% |
| 0.6 SD | 99% | 93% | 21% | 97% | 31% |
*
RRR=relative risk reduction. SD=standard deviation. Δ=difference