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. Author manuscript; available in PMC: 2014 Jul 18.
Published in final edited form as: Sci Transl Med. 2013 Mar 6;5(175):175ra31. doi: 10.1126/scitranslmed.3004986

Fig. 1. PDHC phosphorylation and activity after drug treatment of human wild-type (WT) fibroblasts.

Fig. 1

A. Western blotting of BA1054 fibroblasts treated with 0.25, 0.5, or 1 mM of phenylbutyrate for 24 hours, or untreated. The images are representative of two independent experiments. B. The average band intensities of phosphorylated E1 normalized for total E1 from two independent experiments. C. Two independent fibroblast cell lines (BA1054 and BA1020) were treated with phenylbutyrate at 1 mM for 24 hours before measurement of PDH enzyme activity. *: p<0.05; **: p<0.01.