Table 3. Subgroup analysis of efficacy outcomes according to age, performance status and extent of disease.
| Subgroup | ORR, % | TTP, months | OS, months |
|---|---|---|---|
|
Age | |||
| 70–75 years (n=25) | 40 | 7.7 | 24.3 |
| >75 years (n=43) |
49 |
13.5 |
20.1 |
|
ECOG performance status | |||
| 0 (n=32) | 34 | 10.4 | 24.3 |
| 1 (n=36) |
56 |
12.7 |
16.7 |
|
No. of organs with metastases | |||
| 1 (n=22) | 46 | 10.6 | NA |
| 2 (n=18) | 33 | 7.4 | 13.5 |
| ⩾3 (n=28) | 54 | 13.8 | 20.4 |
Abbreviations: ECOG=Eastern Cooperative Oncology Group; NA=not available; ORR=objective response rate; OS=overall survival; TTP=time to progression.
All P>0.05.