Table 4. Adverse events occurring in >10% of patients.
| Adverse events, n (%) | Any grade | Grade 1 | Grade 2 | Grade 3 | Grade 4 |
|---|---|---|---|---|---|
| Neutropenia |
17 (25) |
8 (12) |
6 (9) |
3 (4) |
0 |
| Thrombocytopenia |
9 (13) |
1 (1) |
7 (10) |
1 (1) |
0 |
| Anaemia |
10 (15) |
6 (9) |
4 (6) |
0 |
0 |
| Diarrhoea |
42 (62) |
16 (24) |
14 (21) |
11 (16) |
1 (1) |
| Nausea |
16 (24) |
9 (13) |
6 (9) |
1 (1) |
0 |
| Vomiting |
22 (32) |
14 (21) |
5 (7) |
3 (4) |
0 |
| Mucositis |
22 (32) |
11 (16) |
9 (13) |
2 (3) |
0 |
| Abdominal pain |
8 (12) |
5 (7) |
1 (1) |
2 (3) |
0 |
| Anorexia |
20 (29) |
9 (13) |
9 (13) |
2 (3) |
0 |
| Hyporexia |
7 (10) |
5 (7) |
2 (3) |
0 |
0 |
| Hand–foot syndrome |
13 (19) |
6 (9) |
2 (3) |
5 (7) |
0 |
| Asthenia |
42 (62) |
15 (22) |
16 (24) |
11 (16) |
0 |
| Neurotoxicity |
23 (34) |
17 (25) |
6 (9) |
0 |
0 |
| Paraesthesia |
15 (22) |
13 (19) |
2 (3) |
0 |
0 |
| Neuropathy | 11 (16) | 5 (7) | 3 (4) | 3 (4) | 0 |