Table 1. Hematological Variables Before and After Hydroxyurea Treatment a,b,c.
| Variables | Pre-HU Treatment | Post-HU Treatment | P Value |
|---|---|---|---|
| Pre-transfusion Hb, g/dL | 9.53 ± 1.1 | 8.28 ± 0.73 | < 0.001 |
| Transfusion, mL/kg/d | 0.71 ± 0.21 | 0.43 ± 0.21 | < 0.001 |
| Transfusion interval, d | 14 ± 3 | 28 ± 7 | 0.012 |
| Median | 15 | 16.2 | |
| Serum Ferritin, ng/mL | 2498.25 ± 1980.77 | 2214.72 ± 1950.44 | 0.021 |
| Median | 1864 | 1463 | |
| Hb F, g/dL | 1.1 ± 0.3 | 5 ± 1.1 | < 0.001 |
a Abbreviations: HbF, hemoglobin F; HU, hydroxyurea.
b Data are presented as mean ± SD.
c Serum ferritin levels and transfusion interval did not show normal distribution at the studied population; thus, nonparametric test was done, and median value was also reported for both.