. Author manuscript; available in PMC: 2014 Jul 18.

Published in final edited form as: Cancer Prev Res (Phila). 2010 Feb 23;3(3):290–300. doi: 10.1158/1940-6207.CAPR-09-0199

Table 1.

Immunohistochemical expression of phosphorylated S6 ribosomal protein and serine phosphorylated IRS-1 in normal proliferative endometrium, endometrial CAH and endometrial endometrioid carcinoma, grade 1. All of these tissues expressed IRS-1 and/or IRS-2. Results are expressed as the number of cases with 2+ or 3+ immunohistochemical expression (n; %). Correlation between expression of phospho-(S235) S6 and phospho-(S636/639) IRS-1 was determined by Pearson’s correlation (p<0.025). ^* Statistically significant as compared to normal endometrium at the p<0.001 level by χ2-analysis.

Group	Phospho-(S235) S6	Phospho-(S636/639) IRS-1
Normal (n=6)	1 (17%)	6 (100%)
CAH (n=25)	24 (96%)^*	5 (20%)
EEC Grade 1 (n=10)	9 (90%)^*	2 (18%)

statistically significant as compared to normal endometrium at the p<0.001 level by x2-analysis.