. Author manuscript; available in PMC: 2014 Jul 18.

Published in final edited form as: Int J Radiat Oncol Biol Phys. 2013 Mar 28;86(3):540–545. doi: 10.1016/j.ijrobp.2012.12.029

Table 2.

Quantitative Toxicity by Sunitinib (S) Dose-level: pts (patients); LI (Lead-in); DLT (dose-limiting toxicity), Hem (hematological), GI (gastrointestinal);

Sunitinib dose	# pts	LI Tox	Withdrew	Completed S+XRT	Post-XRT S completed	S Dose-reduced	DLT (S+XRT)	Grade/Type (n)
12.5mg	7	1	1	6	6	0	0	G4 Fatigue (1)
25mg	3	0	0	3	3	0	0	-
37.5mg	4	4	1	3	3	3	0	G3 Hem(3) G2 Hem(1)
37.5mg^*	3	0	0	3	2	2	2	G3 GI (n=2) G3 Fatigue (n=1)
Totals	17	5	2	15	14	5	2	8 events (7 pts)

without concurrent bicalutamide.