Table 2. Modifications brought to the numbering scheme.
Modifications brought to the numbering scheme in the light of new and atypical sequences. LFR3, light chain framework 3; HFR3, heavy chain framework 3. CDR-H3 insertion positions H100uvw were not required in the present dataset, but were added for the technical continuity up to the pre-existing positions H100xyz and for future use. Thus 3U1S has a CDR-H3 length of 31 residues.
| Locus | Numbering scheme addition |
Maximum CDR length |
Structures with the new maximum length |
CDR extents |
|---|---|---|---|---|
| CDR-L1 | – | 17 | N/A | L24-L34 |
| CDR-L2 | L51abcd | 11 | 2GSG, 2H32, 2H3N, 2OTU, 2OTW, 2QHR, 3FFD |
L50-L56 |
| LFR3 | L67ab | N/A | 1PW3 | N/A |
| CDR-L3 | L95cd | 13 | 2GSG, 2OTU, 2QHR, 3FFD, 3MLW |
L89-L97 |
| CDR-H1 | H31cdefghijk | 24 | 3K3Q | H23–H35 |
| CDR-H2 | H52ef | 15 | 3TWC, 3TYG | H50–H58 |
| HFR3 | H74abcdefg | N/A | 3SE8 | N/A |
| CDR-H3 | H100nopqrstuvw | 34 | 3U1S | H95-H102 |