Table 8. Summation of clustered lengths per CDR.

(A) Summation of clustered lengths per CDR, with population, non-redundant sequences, number of clusters and outliers information. CDR lengths that were clustered for the first time are highlighted in bold/italics. (B) The complete CDR-H3 conformation, using the H95-H102 extents definition, has not been extensively clustered before; therefore only lengths that were not considered in Kuroda et al. (2009) are noted as new for conformity with the literature. CDR-H3 lengths 4 and 24 are marked with an asterisk as the corresponding structures are also found in North, Lehmann & Dunbrack (2011), but acknowledged as 2 residues longer, due to different CDR-H3 extents (H93-H102).

(A)
CDR	Observed lengths (new lengths)	Total structure population	Unique sequences	Level-1 clusters	Level-1 only structure population	Singletons/outliers
L1	7	2	1	1	2	0
	9	10	4	2	10	0
	10	127	28	1	126	1
	11	1,042	180	4	1,033	9
	12	82	26	4	81	1
	13	81	26	3	81	0
	14	207	25	7	193	14
	15	80	34	2	32	48
	16	352	74	5	319	33
	17	172	36	1	171	1
Total	10 lengths	2,155	434	30	2,048	107
CDR	Observed lengths	Total structure population	Unique sequences	Level-1 clusters	Level-1 only structure population	Singletons/outliers
L2	7	2,161	278	3	2,159	2
	11	13	3	2	13	0
Total	2 lengths	2,174	281	5	2,172	2
CDR	Observed lengths (new lengths)	Total structure population	Unique sequences	Level-1 clusters	Level-1 only structure population	Singletons/outliers
L3	5	10	4	1	10	0
	7	5	2	1	5	0
	8	138	43	6	136	2
	9	1,725	358	6	1,720	5
	10	113	27	12	107	6
	11	142	38	9	135	7
	12	19	6	4	19	0
	13	12	2	3	11	1
Total	8 lengths	2,164	480	42	2,143	21
CDR	Observed lengths (new lengths)	Total structure population	Unique sequences	Level-1 clusters	Level-1 only structure population	Singletons/outliers
H1	10	6	2	1	6	0
	12	2	2	0	0	2
	13	1,845	450	11	1,681	164
	14	72	17	1	70	2
	15	128	29	3	125	3
	16	3	2	1	2	1
	24	1	1	0	0	1
Total	7 lengths	2,057	503	17	1,884	173
(B)
CDR	Observed lengths (new lengths)	Structure population	Unique sequences	Level-1 clusters	Level-1 only structure population	Singletons/outliers
H2	8	6	2	1	6	0
	9	436	117	6	435	1
	10	1,508	381	10	1,356	152
	11	3	3	0	0	3
	12	171	38	4	171	0
	15	6	3	2	5	1
Total	6 lengths	2,130	544	23	1,973	157
CDR	Observed lengths (new lengths)	Structure population	Unique sequences	Level-1 clusters	Level-1 only structure population	Singletons/outliers
H3	3	18	4	1	18	0
	4*	38	12	2	36	2
	5	93	28	6	85	8
	6	33	12	3	30	3
	7	97	41	7	69	28
	8	168	46	7	141	27
	9	181	55	8	132	49
	10	377	98	35	292	85
	11	231	64	26	151	80
	12	206	51	21	174	32
	13	130	42	22	105	25
	14	128	40	19	104	24
	15	96	23	18	81	15
	16	40	16	8	28	12
	17	28	14	6	19	9
	18	37	11	6	31	6
	19	48	12	9	46	2
	20	13	4	3	13	0
	21	10	1	1	10	0
	22	33	4	2	31	2
	23	1	1	0	0	1
	24*	12	2	2	12	0
	25	1	1	0	0	1
	28	12	2	1	12	0
	31	1	1	0	0	1
Total	25 lengths	2,032	585	213	1,620	412
Cumulative total (all CDRs)	58 lengths	12,712	2,827	330	11,840	872