Table 9. Summary table of Phase-1 prediction results over all test data belonging to non-unique-cluster lengths, for CDR-H1 and -H2.
Totals include novel conformations.
| DCP signatures | Canonical templates | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| CDR/Length | Accurately predicted conformations |
Uncertain predictions |
False predictions |
Novel
conformations |
Accurately predicted conformations |
Uncertain predictions |
False predictions |
New CDR sequences in test set (not present in training set) |
Unique CDR sequences in training set |
| CDR-H1-13 | 178/201 (89%) | 0/201 | 8/201 (4%) | 16/201 (8%) | 153/201 (76%) | 24/201 (12%) | 8/201 (4%) | 135/201 (67%) | 419 |
| CDR-H1-15 | 5/9 (56%) | 0/9 | 2/9 (22%) | 2/9 (22%) | 3/9 (33%) | 2/9 (22%) | 2/9 (22%) | 8/9 (89%) | 27 |
| Total | 183/210 (87%) | 0/210 | 10/210 (5%) | 18/210 (9%) | 156/210 (74%) | 26/210 (12%) | 10/210 (5%) | 143/210 (68%) | 446 |
| CDR-H2-9 | 41/41 (100%) | 0/41 | 0/41 | 0/41 | 27/41 (66%) | 14/41 (34%) | 0/41 | 30/41 (73%) | 117 |
| CDR-H2-10 | 145/168 (86%) | 6/168 (4%) | 14/168 (8%) | 3/168 (2%) | 89/168 (53%) | 60/168 (36%) | 16/168 (10%) | 128/168 (76%) | 350 |
| CDR-H2-12 | 7/8 (88%) | 0/8 | 0/8 | 1/8 (13%) | 7/8 (88%) | 0/8 | 0/8 | 4/8 (50%) | 39 |
| Total | 193/217 (89%) | 6/217 (3%) | 14/217 (6%) | 4/217 (2%) | 123/217 (57%) | 74/217 (34%) | 16/217 (7%) | 162/217 (75%) | 506 |