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. Author manuscript; available in PMC: 2015 Mar 3.
Published in final edited form as: FEBS Lett. 2014 Feb 1;588(5):829–835. doi: 10.1016/j.febslet.2014.01.046

Figure 2. MAPRE1 is increased in early carcinogenesis and the uninvolved mucosa.

Figure 2

A) EB1 expression at a pre-neoplastic time point of the AOM rat model (10 weeks), and in the uninvolved mucosa (“field”) of the AOM rat model (tumor-bearing time point, 37 weeks) and the Pirc rat model using qRT-PCR. Standard error bars shown, *p <0.05. B) Protein expression of EB1 and APC (c-terminus) in the early colon carcinogenesis model. C) Protein expression of EB1 and APC (c-terminus) in the uninvolved mucosa in both a chemically induced rat model (AOM) and genetic Pirc rat model of colon carcinogenesis. D) Quantification of protein expression confirm reduced APC levels with increased EB1 levels, *p <0.1.