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. Author manuscript; available in PMC: 2015 Jul 8.
Published in final edited form as: Circulation. 2014 Jun 9;130(2):161–167. doi: 10.1161/CIRCULATIONAHA.113.005425

Table 4.

Lifetime Attributable Risk of Cancer above Baseline According to Operative Group

Cancer Cases / 100,000 Exposed
Median (LL, UL) 5,95%
ASD 6 (4,11) 2,836
VSD 12 (8,20) 2, 846
ASO 13 (9,22) 4,180
TOF 14 (9,23) 2, 1311
AVCD 20 (13,32) 2, 698
Norwood 799 (536,1354) 15, 3043
Cardiac transplant 1677 (1125,2815) 405, 6467

Total 65 (43, 112) 2, 2319

LL = lower limit; UL = upper limit; these values were calculated using the BEIR VII confidence intervals. A LL and UL was calculated for each patient, and the data presented represent the median cohort values for these limits. The 5% and 95% estimates represent the overall cohort 5% and 95% limits calculated using the standard BEIR VII age and sex specific cancer estimates. ASD = atrial septal defect; VSD = ventricular septal defect; AVCD = atrioventricular canal defect; TOF = tetralogy of Fallot; ASO = atrial switch operation.