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FAN1 Oligomeric Status
(A) Overlay of S200 gel filtration traces of FAN1 orthologs against molecular weight standards.
(B) AUC sedimentation velocity run of mFAN1 at 4°C demonstrating a monomeric species with table of FAN1 AUC-derived parameters inset.
(C) S200 gel filtration trace of trypsin-treated hFAN1_360 showing the elution of a single protein peak. An SDS-PAGE gel of fractions across the peak is inset demonstrating the presence of three coeluting protein fragments.
