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. Author manuscript; available in PMC: 2015 Apr 1.
Published in final edited form as: J Int Neuropsychol Soc. 2014 Mar 12;20(4):422–433. doi: 10.1017/S1355617714000113

Figure 1. Regions of interest for PET and fMRI data sampling.

Figure 1

Binary masks with which PiB (blue), FDG (green), and fMRI (red, purple where intersects with PiB mask) were sampled. The masks are overlaid on the SPM single subject atlas conformed to MNI space at y-plane locations −15 −10 −5 0 5 10 15. The PiB mask was derived using the precuneus label in the WFU_PickAtlas toolbox (Maldjian et al., 2003); the FDG mask was taken from the PCC template in the Meta-ROI suite developed by ADNI;15 and the fMRI mask was empirically generated using data from an independent set of Stables (n=90) and Decliners (n=34) who had completed the fMRI task as part of enrolment in another imaging study.

PiB= Pittsburgh Compound B; FDG= fluorodeoxyglucose; fMRI=functional magnetic resonance imaging; SPM=statistical parametric mapping; MNI=Montreal Neurological Institute; WFU=Wake Forest University; PCC=posterior cingulate cortex; ROI=region of interest; ADNI=Alzheimer’s Disease Neuroimaging Initiative.