TABLE 4.
Pathologic Findings After Elective MIE With Either a Cervical (MIE-Neck) or Intrathoracic (MIE-Chest) Anastomosis
| Tumor Specific Variables, if Malignant Disease | MIE-Neck, n = 462 (48%) | MIE-Chest, n = 498 (52%) | Total, n = 960 | P |
|---|---|---|---|---|
| Tumor location, n (%) | ||||
| Proximal or middle esophagus | 44 (10) | 16 (3) | 60 (7) | <0.001 |
| Distal esophagus or gastroesophageal junction | 379 (90) | 470 (97) | 849 (93) | |
| Clinical stage before initial therapy (if malignant), n (%) | ||||
| Stage 0 | 71 (18) | 24 (7) | 95 (13) | <0.001 |
| Stage I | 65 (16) | 70 (20) | 135 (18) | |
| Stage IIa | 57 (14) | 75 (21) | 132 (17) | |
| Stage IIb | 67 (17) | 40 (11) | 107 (14) | |
| Stage III | 113 (29) | 127 (35) | 240 (32) | |
| Stage IV | 24 (6) | 24 (7) | 48 (6) | |
| Squamous tumor type, n (%) | 61 (13) | 44 (9) | 105 (11) | 0.030 |
| Adenocarcinoma tumor type, n (%) | 316 (68) | 411 (83) | 727 (76) | <0.001 |
| Tumor invasion at esophagectomy, T3 or T4, n (%) | 180 (39) | 221 (45) | 401 (42) | 0.067 |
| Nodal metastasis at esophagectomy, n (%) | 178 (39) | 239 (49) | 417 (44) | 0.003 |
| Adequacy of cancer resection | ||||
| Negative margins, n (%) | 453 (98) | 486 (98) | 939 (98) | 0.623 |
| Number of lymph nodes examined, median (IQR) | 19 (13–26) | 23.5 (17–31) | 21 (15–29) | <0.001 |