Table 1. Immune responses induced by FliC-displaying L. casei and purified flagellin.
Dose (i.g.) | Dosage (per mouse) | α-FliC sIgA | α-FliC IgG | Specific IFN-γ | Protection |
LCF | 1 × 1010 cfu | – | – | +++ | + |
LCF | 1 × 109 cfu | – | – | ++ | ND |
LCN + Flagellin | 1 × 1010 cfu + 5 μg | – | – | + | ND |
LCN | 1 × 1010 cfu | – | – | – | – |
Flagellin | 50 μg | + | + | ++ | + |
Flagellin | 5 μg | – | – | + | ND |
Flagellin | 0.5 μg | – | – | – | ND |
PBS | – | – | – | – |