Table 2. Immunological properties of recombinant L. casei displaying Salmonella antigens.

Recombinant L. casei	In vitro assays	Route of immunization	Immune responses	Protection against SE	References
FliC	IL-8 from Caco-2 cells	i.g.	IFN-γ	Yes	19
cSipC	ND	i.p.	α-cSipC IgG	ND	28
FliC-cSipC	IL-8 from Caco-2 cells	i.p./i.g.	α-cSipC/FliC IgG IFN-γ	Yes	28, Kajikawa et al. unpublished data
cSipC-FliC	IL-8 from Caco-2 cells	i.p.	α-cSipC/FliC IgG	ND	28
OmpC	Decrease in TNF-α from RAW264.7 cells	ND	ND	ND	27
FliC-OmpC	ND	i.g.	IFN-γ	Yes	Kajikawa et al. unpublished data