Table 3. Association between serum phosphorus and all-cause mortality.
Serum phosphorus range, mg/dl | Number of subjects | Mortality per 1000 person-years | Unadjusted | Model 1 | Model 2 | Model 3 | |
---|---|---|---|---|---|---|---|
Quartile 1 | ≤3.3 | 2979 | 19.8 | Ref | Ref | Ref | Ref |
Quartile 2 | >3.3 to 3.7 | 2947 | 23.2 | 1.18 (0.94–1.47) | 1.12 (0.88–1.43) | 1.20 (0.94–1.54) | 1.22 (0.95–1.56) |
Quartile 3 | >3.7 to 4.1 | 2577 | 20.3 | 1.01 (0.80–1.29) | 0.96 (0.75–1.25) | 1.01 (0.78–1.32) | 1.00 (0.76–1.32) |
Quartile 4 | >4.1 | 2169 | 22.7 | 1.12 (0.88–1.42) | 1.01 (0.77–1.33) | 1.02 (0.77–1.36) | 1.00 (0.75–1.33) |
Model 1: adjusted for demographics (age, gender, race/ethnicity, highest education), year of screening, cardiovascular risk factors (diabetes, hypertension, dyslipidemia, current tobacco use, body mass index), and severity of chronic kidney disease (CKD; estimated glomerular filtration rate (eGFR) and albuminuria).
Model 2: adjusted model 1 plus laboratory parameters (plasma glucose, calcium, parathyroid hormone, and hemoglobin).
Model 3: adjusted model 2 plus CKD awareness and health insurance.