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. 2014 Apr 4;23(16):4215–4231. doi: 10.1093/hmg/ddu140

Figure 3.

Figure 3.

Tbx1, Lhx2, Lrrn1 and Chrdl1 expression in the core mesoderm in Tbx1+/+ versus Tbx1−/− embryos at E9.5 and E10.5. Lateral views of whole-mount in situ hybridization of Tbx1+/+ and Tbx1−/− embryos at E9.5 and E10.5 with antisense probes for Tbx1 (Wt only), Lhx2, Lrrn1 and Chrdl1. Coronal tissue sections from a subset of the whole-mount stained embryos are shown adjacent to the whole-mount images. Chrdl1 is not expressed in the core mesoderm in Tbx1+/+ embryos at E9.5; thus, no images are shown for Tbx1−/− embryos at this stage. Lhx2, Lrrn1 and Chrdl1 were not expressed in the core mesoderm in Tbx1−/− embryos so only whole-mount images are shown.