Table 1. Percent GFP in hematopoietic populations from FlkSwitch mice.
HSC | ST-HSCF | MPPF | CMP | GMP | MEP | GM | EP | Plt | CLP** | B cell** | T cell* | |
---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | 0 | 1 | 6 | 7 | 7 | 7 | 10 | 7 | 6 | 15 | 38 | 23 |
2 | 0 | 2 | 7 | 6 | 6 | 9 | 10 | 6 | 8 | 14 | 32 | 20 |
3 | 0 | 5 | 12 | 12 | 12 | 13 | 11 | 12 | 13 | 27 | 47 | 23 |
4 | 0 | 5 | 12 | 10 | 12 | 12 | 13 | 12 | 13 | 27 | 50 | 28 |
5 | 0 | 4 | 20 | 18 | 20 | 19 | 21 | 18 | 21 | 25 | 44 | 19 |
6 | 0 | 63 | 89 | 91 | 90 | 89 | 86 | 86 | 92 | 91 | 97 | 94 |
7 | 0 | 51 | 90 | 88 | 89 | 91 | 90 | 88 | 93 | 91 | 99 | 92 |
8 | 0 | 44 | 90 | 88 | 89 | 90 | 89 | 90 | 92 | 97 | 98 | 96 |
9 | 0 | 61 | 92 | 92 | 92 | 93 | 92 | 92 | 91 | 96 | 100 | 95 |
10 | 0 | 37 | 94 | 94 | 94 | 94 | 93 | 93 | 93 | 98 | 100 | 97 |
11 | 0 | 68 | 95 | 94 | 93 | 92 | 92 | 93 | 86 | 98 | 99 | 94 |
12 | 0 | 45 | 95 | 95 | 95 | 97 | 94 | 97 | 98 | 100 | 100 | 96 |
13 | 0 | 74 | 96 | 94 | 94 | 93 | 94 | 94 | 93 | 99 | 100 | 94 |
14 | 0 | 60 | 97 | 98 | 99 | 99 | 98 | 98 | 96 | 99 | 100 | 100 |
The differences between MPPF versus CLP, B, and T cells were significant (p<0.001; p<0.001, and p<0.01, respectively), by Wilcoxon Signed Rank test. HSC and ST-HSCF were also significantly different from MPPF and all other populations. No other comparisons to MPPF were significantly different. Abbreviations as in Figure 1. See also Figure S2.