Table 4.
Effect of yam on AOM-induced colonic ACF formation in rats
| AOM | AOM+2%Y | AOM+5%Y | |
|---|---|---|---|
| Total no. of ACF/colon | 171.5±55.1a | 118.6±36.8ab | 110.8±23.8b |
| Crypt multiplicity of ACF | |||
| 1 crypt | 39.1±14.4ns | 27.5±14.0 | 25.4±6.9 |
| 2 crypts | 45.0±16.7ns | 37.9±17.0 | 28.5±10.4 |
| 3 crypts | 34.4±11.8a | 24.9±7.9ab | 19.8±6.3b |
| ≥4 crypts | 53.0±16.3a | 29.2±11.9b | 35.8±17.1ab |
| Distribution of ACF | |||
| Proximal colon | 81.8±28.4a | 47.5±16.2b | 40.8±30.4b |
| Middle colon | 64.0±25.5ns | 49.0±18.0 | 41.2±27.1 |
| Distal colon | 25.4±12.3ns | 22.4±11.5 | 27.4±5.6 |
Values are mean±SD (n=6). Values are the number of ACF.
Different superscripts (a,b) within a row indicate significant differences among groups (P <0.05).
ns
not significant.