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. 2014 Jun;19(2):82–88. doi: 10.3746/pnf.2014.19.2.082

Table 7.

Effect of yam on gene expression of NF-κB, inflammatory enzymes and cytokines in the colonic mucosa of rats

AOM AOM+2%Y AOM+5%Y
NF-κB/p65
 ΔCT 3.36±0.35a 4.28±0.44b 4.16±0.60b
 2−ΔΔCT 1.00 0.53 0.57
iNOS
 ΔCT 8.62±0.61a 11.2±0.39b 11.5±0.97b
 2−ΔΔCT 1.00 0.16 0.14
COX-2
 ΔCT 5.70±1.27a 10.8±1.91b 9.42±0.50b
 2−ΔΔCT 1.00 0.03 0.08
TNF-α
 ΔCT 3.29±1.24a 3.07±0.50a 5.42±0.52b
 2−ΔΔCT 1.00 1.16 0.35
IL-1β
 ΔCT 3.98±0.48a 4.09±0.45a 5.20±0.90b
 2−ΔΔCT 1.00 0.93 0.43

Values are mean±SD (n=6).

Different superscripts (a,b) within a row indicate significant dif ferences among groups (P <0.05).

ΔCT, mean of CT value for the target gene–mean of CT value for β-actin; 2−ΔΔT, differential gene expression in the target sample compared to the normal sample counterpart.