Skip to main content
. 2014 Jul 18;9(7):e102388. doi: 10.1371/journal.pone.0102388

Table 1. Clinicopathological features of patients harboring ERBB4 variants −782G>T or −815A>T.

−782 G>T −815 A>T
GG GT AA AT
n (%) n (%) P-value n (%) n (%) P-value
Frequency 872 (98) 23 (2) 879 (99) 12 (1)
pT
≤20 mm 364 (98) 9 (2) 366 (99) 5 (1)
>20 mm 508 (98) 13 (2) 0.938 512 (99) 7 (1) 0.999
pN
negative 91 (97) 3 (3) 95 (99) 1 (1)
positive 781 (98) 20 (2) 0.726 784 (99) 11 (1) >0.999
Histology
ductal 682 (97) 19 (3) 689 (99) 9 (1)
lobular/other 190 (98) 4 (2) 0.799 190 (98) 3 (2) 0.729
Grade
1 121 (94) 8 (6) 0.018 125 (98) 3 (2) 0.408
2 352 (98) 7 (2) 356 (99) 3 (1)
3 362 (98) 7 (2) 361 (98) 6 (2)
ER
- 242 (97) 7 (3) 243 (99) 3 (1)
+ 630 (98) 16 (2) 0.777 636 (99) 9 (1) >0.999
PR
- 373 (97) 10 (3) 371 (98) 6 (2)
+ 498 (97) 13 (3) 0.959 507 (99) 6 (1) 0.590
ERBB2
- 675 (97) 19 (3) 678 (77) 12 (2)
+ 197 (98) 4 (2) 0.555 201 (23) 0 (0) 0.079
ErbB4 IHC
negative 138 (96) 6 (4) 140 (97) 4 (3)
positive 697 (98) 15 (2) 0.145 701 (99) 7 (1) 0.098