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. 2014 Jul 18;9(7):e102883. doi: 10.1371/journal.pone.0102883

Table 2. Common clinical characteristics that may influence medical providers' decision of referral HIV-infected patients for hepatitis C treatment consideration.

Clinical characteristic Referred n = 303 (%) Non-referred n = 259 (%) P value
Not engaged in care 31 (10) 95 (37) <0.0001
Unstable housing 22 (7) 39 (15) 0.003
Most recent CD4 cell count ≤200 cells/mm3 51 (17) 70 (27) 0.003
Ongoing neuropsychiatric disorders 143 (47) 62 (24) <0.0001
Ongoing drug and/or alcohol abuse 118 (39) 75 (29) 0.013
Decompensated cirrhosis 34 (11) 21 (8) 0.22
Active opportunistic infections 5 (2) 9 (4) 0.17
Platelets ≤50,000/mm3 * 11 (4) 6 (2) 0.37
Anemia ≤10 g/dL* 11 (4) 10 (4) 0.89
Malignancy other than hepatocellular carcinoma 6 (2) 15 (6) 0.02
Cardiovascular disease 16 (5) 13 (5) 0.89
Chronic kidney disease 3b (<45 mL/min/1.73m2) 10 (3) 13 (5) 0.31
Other medical comorbidity that takes clinical care priority 26 (9) 14 (5) 0.14

*Two patients in the HCV non-referred group did not have available hemoglobin and platelet values.