Table 1. Clinical characteristics of the study population.
No. (%)a | |||
Characteristic | Bronchiectasis (n = 144) | Healthy subjects (n = 80) | P value* |
Age, mean (SD), y | 46.2 (13.6) | 47.1 (12.3) | 0.62 |
Female sex | 89 (61.8) | 47 (58.8) | 0.65 |
Body-mass index, mean (SD), kg/m2 | 20.3 (3.1) | 23.4 (2.7) | <0.001 |
Smoking status | <0.001 | ||
Current | 3 (2.1) | 22 (27.5) | |
Former | 20 (13.9) | 2 (2.5) | |
Never | 121 (84.0) | 56 (70.0) | |
Marital status | 0.12 | ||
Never married | 15 (10.4) | 14 (17.5) | |
Married/cohabiting | 119 (82.6) | 65 (81.2) | |
Divorced/separated | 4 (2.8) | 1 (1.3) | |
Widowed | 6 (4.2) | 0 (0.0) | |
Education | |||
Highest completed level | 66 (45.9) | 38 (47.1) | |
Less than high school | 42 (29.2) | 24 (30.2) | |
High school graduate or equivalent | 36 (25.0) | 18 (22.7) | |
College graduate or above | |||
Employment status | 0.001 | ||
Working full time or part time | 70 (48.6) | 51 (63.8) | |
Not working due to health | 15 (10.4) | 0 (0.0) | |
Student | 2 (1.4) | 6 (7.5) | |
Housewife | 9 (6.3) | 4 (5.0) | |
Seeking work/not work for other reasons | 48 (33.3) | 19 (23.8) | |
Anxiety and Depression | |||
HADS-Anxiety score≥8 | 67 (46.5) | 5 (6.3) | <0.001 |
HADS-Depression score≥8 | 43 (29.9) | 8 (10.0) | 0.003 |
Pulmonary function, mean (SD) | |||
FEV1 pred% | 67.4 (22.6) | … | … |
FVC pred% | 76.5 (19.4) | … | … |
Rhinosinusitis | 40 (27.8) | … | … |
Cause of bronchiectasis | |||
Idiopathic/post infective | 102 (70.8) | … | … |
Humoral immune deficiency | 10 (6.9) | … | … |
COPD or asthma | 9 (6.3) | … | … |
Kartagener syndrome | 3 (2.1) | … | … |
Previous ABPA | 2 (1.4) | … | … |
Rheumatoid arthritis | 2 (1.4) | … | … |
Others | 16 (11.1) | … | … |
Abbreviations: ABPA = Allergic bronchopulmonary aspergillosis; COPD = Chronic obstructive pulmonary disease; FEV1 = Forced expiratory volume in one second; FVC = Forced vital capacity; HADS = Hospital anxiety and depression scale; pred = Predicted values; SD = Standard deviation. a Unless otherwise specified, values represent no. (%) of participants.
*Unpaired t test or chi-square test was used to compare variables in bronchiectasis patients vs. controls as appropriate.