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. Author manuscript; available in PMC: 2014 Jul 18.
Published in final edited form as: J Allergy Clin Immunol. 2013 Apr 25;131(6):1586–1593. doi: 10.1016/j.jaci.2013.02.038

FIG 3.

FIG 3

Family J017: STAT3 sequence for a control subject, subject J017.10, and subject J017.3. A, cDNA sequencing (c.1145 G>A). The control shows only the G allele in the boxed region. Subject J017.10 demonstrates 2 alleles with WT and mutant bases at similar heights, roughly half the height of the control subject. Subject J017.3 has decreased WT 1145G compared with control values and a small 1145G>A peak seen near the baseline. The arrow points to the mutant green A peak. B, Genomic DNA sequencing. The common C/G SNP found within intron 13 shows 2 separate and equally abundant alleles in subject J017.3, whereas only the G allele is seen in the control subject.